Substrate: HSF 1 (Transcription factor)
Seq-ID: P38532 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity		 cytoplasm,
protein complex,
pronucleus		 protein amino acid phosphorylation,
transcription,
negative regulation of cell proliferation,
negative regulation of tumor necrosis factor production,
response to heat,
embryonic process involved in female pregnancy,
embryonic placenta development,
positive regulation of multicellular organism growth,
spermatogenesis,
regulation of transcription, DNA-dependent,
response to lipopolysaccharide
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 415 VDTSALLDLFSPSVTMPDMSL PLK1 15661742
LTP
0.99
 - Vert_HS_TF
0.46
 - low

Substrate: HSF 1 (Transcription factor)
Seq-ID: Q00613 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-1785958   STUB1_HUMAN
MINT-6743391   STRAP_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding transcription factor activity,
protein binding		 cytoplasm transcription,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 121 LLENIKRKVTSVSTLKSEDIK MAPKAPK2 16278218
LTP
0.22
 - HSF_DNA-bind
0.31
 - high
T 142 IRQDSVTKLLTDVQLMKGKQE CK2_group 12659875
LTP
0.15
 - HSF_DNA-bind
0.33
 - high
T 142 IRQDSVTKLLTDVQLMKGKQE CK2_alpha 12659875
LTP
0.15
 - HSF_DNA-bind
0.33
 - high
T 142 IRQDSVTKLLTDVQLMKGKQE - 15302935
HTP
0.15
 - HSF_DNA-bind
0.33
 - high
S 230 HSMPKYSRQFSLEHVHGSGPY CaM-KII_group 11447121
LTP
1.00
 - -
0.54
 - high
S 230 HSMPKYSRQFSLEHVHGSGPY CaM-KII_alpha 11447121
LTP
1.00
 - -
0.54
 - high
S 230 HSMPKYSRQFSLEHVHGSGPY - 15302935
HTP
1.00
 - -
0.54
 - high
S 292 GSIDERPLSSSPLVRVKEEPP - 15760475
LTP
0.03
 - Vert_HS_TF
0.82
 - high
S 303 PLVRVKEEPPSPPQSPRVEEA GSK-3_group 12665592
LTP
1.00
 MOD_GSK3_1
 - Vert_HS_TF
0.93
 - high
S 303 PLVRVKEEPPSPPQSPRVEEA - 15302935
HTP
1.00
 MOD_GSK3_1
 - Vert_HS_TF
0.93
 - high
S 303 PLVRVKEEPPSPPQSPRVEEA - 17081983
HTP
1.00
 MOD_GSK3_1
 - Vert_HS_TF
0.93
 - high
S 303 PLVRVKEEPPSPPQSPRVEEA - 18669648
HTP
1.00
 MOD_GSK3_1
 - Vert_HS_TF
0.93
 - high
S 307 VKEEPPSPPQSPRVEEASPGR MAPK_group 8940068
LTP
1.00
 MOD_ProDKin_1
 - Vert_HS_TF
0.96
 - high
S 307 VKEEPPSPPQSPRVEEASPGR - 15302935
HTP
1.00
 MOD_ProDKin_1
 - Vert_HS_TF
0.96
 - high
S 307 VKEEPPSPPQSPRVEEASPGR - 17081983
HTP
1.00
 MOD_ProDKin_1
 - Vert_HS_TF
0.96
 - high
S 307 VKEEPPSPPQSPRVEEASPGR - 18669648
HTP
1.00
 MOD_ProDKin_1
 - Vert_HS_TF
0.96
 - high
S 314 PPQSPRVEEASPGRPSSVDTL - 15760475
LTP
0.36
 - Vert_HS_TF
0.90
 - high
S 314 PPQSPRVEEASPGRPSSVDTL - 17081983
HTP
0.36
 - Vert_HS_TF
0.90
 - high
S 314 PPQSPRVEEASPGRPSSVDTL - 18220336
HTP
0.36
 - Vert_HS_TF
0.90
 - high
S 319 RVEEASPGRPSSVDTLLSPTA - 15760475
LTP
0.33
 - Vert_HS_TF
0.77
 - high
S 319 RVEEASPGRPSSVDTLLSPTA - 18220336
HTP
0.33
 - Vert_HS_TF
0.77
 - high
T 323 ASPGRPSSVDTLLSPTALIDS - 17081983
HTP
1.00
 - Vert_HS_TF
0.62
 - high
T 323 ASPGRPSSVDTLLSPTALIDS - 18220336
HTP
1.00
 - Vert_HS_TF
0.62
 - high
S 326 GRPSSVDTLLSPTALIDSILR - 15760475
LTP
0.93
 - Vert_HS_TF
0.56
 - high
S 326 GRPSSVDTLLSPTALIDSILR - 18220336
HTP
0.93
 - Vert_HS_TF
0.56
 - high
S 344 ILRESEPAPASVTALTDARGH - 15760475
LTP
0.49
 - Vert_HS_TF
0.77
 - high
S 363 GHTDTEGRPPSPPPTSTPEKC JNK_group 10747973
LTP
0.47
 MOD_ProDKin_1
 - Vert_HS_TF
0.97
 - high
S 363 GHTDTEGRPPSPPPTSTPEKC - 17081983
HTP
0.47
 MOD_ProDKin_1
 - Vert_HS_TF
0.97
 - high
S 363 GHTDTEGRPPSPPPTSTPEKC - 18669648
HTP
0.47
 MOD_ProDKin_1
 - Vert_HS_TF
0.97
 - high
T 367 TEGRPPSPPPTSTPEKCLSVA - 18669648
HTP
0.00
 - Vert_HS_TF
0.88
 - high
S 368 EGRPPSPPPTSTPEKCLSVAC - 18669648
HTP
0.27
 - Vert_HS_TF
0.85
 - high
T 369 GRPPSPPPTSTPEKCLSVACL - 18669648
HTP
0.02
 - Vert_HS_TF
0.83
 - high
S 419 VDTSALLDLFSPSVTVPDMSL - 15760475
LTP
0.97
 - Vert_HS_TF
0.44
 - high
S 444 SSLASIQELLSPQEPPRPPEA - 15760475
LTP
1.00
 - Vert_HS_TF
0.89
 - high

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